Diablo 4 endgame is where the real game starts, and you’ll be wanting to hunt down the best gear in the game, Uniques and Uber Uniques. While these drop from any activity in the game, the drop chance is a lot higher if you target farm endgame bosses on the Boss Ladder, who each have their own individual loot table. Why is it called the Boss Ladder you ask? Because each Boss is summoned using crafting materials, often obtained from the Boss you fought beforehand. The Bosses increase in difficulty, the pinnacle being Andariel and Duriel who drop Uber Uniques. Most players end game will be farming materials to fight Andariel and Duriel.
From Season 4, Patch 1.4.0 introduces Tormented versions of each boss, which as you can assume, are much more difficult but drop better rewards.
Echo of Varshan
Echo of Varshan (Image credit: Jennifer Young – Windows Central)
Varshan was added as a boss fight in Diablo 4 Season 1, Season of the Malignant, and their Echo remains for us to fight as the first Boss on the Ladder. Varshan is also the most efficient boss to farm for the popular Malignant rings .
Varshan will mainly inflict Shadow damage, so stack your build against this with Ameythst Gems and potions.
Where to find Echo of Varshan
Head to the Malignant Burrow under the Tree of Whispers to summon Varshan. (Image credit: Jennifer Young – Windows Central)
How to summon Echo of Varshan
You’ll need the following materials to summon the Echo of Varshan.
Gurgling Head
Trembling Hand
Blackened Femur
Malignant Heart (for World Tier 4 only)
These are basically Varshan’s body parts, and they will fall plentifully as a crafting material by completing Whispers of the Dead.
Tormented Echo of Varshan
2 x Stygian Stones
3 x all of the body parts
Swipe to scroll horizontally
Echo of Varshan Loot Table
General
Barbarian
Druid
Necromancer
Rogue
Sorcerer
Frostburn
Fields of Crimson
Mad Wolf’s Glee
Bloodless Scream
Condemnation
Staff of Endless Rage
Mother’s Embrace
100,000 Steps
Vasily’s Prayer
Deathless Visage
Eyes in the Dark
Esu’s Heirloom
Flesh-weld Rod Trophy (cosmetic)
Gohr’s Devastating Grips
Greatstaff of the Crone
Deathspeaker’s Pendant
Skyhunter
Raiment of the Infinite
Row 3 – Cell 0
Ring of Red Furor
Airidah’s Inexorable Will
Ring of the Sacrilegious Soul
Writhing Band of Trickery
Tal Rasha’s Iridescent Loop
Grigoire, the Galvanic Saint
You’ll need to stack lightning resistance to take on Grigoire in Diablo 4 (Image credit: Jennifer Young – Windows Central)
Grigoire is the first boss you’ll need to farm for materials to go and fight Duriel. He’ll be doing Lightning damage so socket in some Topaz gems to your gear before this fight.
Where to find Grigoire, the Galvanic Saint
Grigoire can be found in the Hall of the Penitent (Image credit: Jennifer Young – Windows Central)
Grigoire is found in the Hall of the Penitent, which is located south of Ked Bardu in the Dry Steppes.
How to summon Grigoire
You’ll need the following materials to summon the Grigoire the Galvanic Saint:
Living Steel x 2 for World Tier 3
Living Steel x 5 for World Tier 4
Living Steel drops when doing Helltide activity, and the most Living Steel can be acquired by opening Tortured Gifts.
Tomented Grigoire
2 x Stygian Stones
3 x Living Steel amounts mentioned above
Swipe to scroll horizontally
Grigoire, the Galvanic Saint Loot Table
General
Barabarian
Druid
Necromancer
Rogue
Sorcerer
Demonbinder (Mount Armor Cosmetic)
Ramaladni’s Magnum Opus
Insatiable Fury
Blood Artisan’s Cuirass
Word of Hakan
Staff of Lam Esen
Penitent Greaves
Rage of Harrogath
Hunter’s Zenith
Howl from Below
Grasp of Shadow
Iceheart Brais
Row 2 – Cell 0
Battle Trance
Waxing Gibbous
Greaves of the Empty Tomb
Windforce
Gloves of the Illuminator
Row 3 – Cell 0
The Butcher’s Cleaver
The Butcher’s Cleaver
Ebonpiercer
Saboteur’s Signet
Flameweaver
Row 4 – Cell 0
Twin Strikes
Earthbreaker
Row 4 – Cell 3
Row 4 – Cell 4
Row 4 – Cell 5
Lord Zir
(Image credit: Jennifer Young – Windows Central)
Lord Zir was the final boss in Season 2’s Season of Blood storyline, and thankfully he was kept for us to slaughter over and over for sweet loot. Blood in itself isn’t an elemental damage type, but Lord Zir’s blood attacks inflict Shadow damage, so you’ll need Amythyst gems and a Potent Elixir of Shadow Resistance.
Where to find Lord Zir
Lord Zir is found at The Darkened Way (Image credit: Jennifer Young – Windows Central)
Lord Zir is found in The Darkened Way, East of Kyovashad in the Fractured Peaks.
How to summon Lord Zir
To summon Lord Zir you’ll need the following:
Exquisite blood drops from Legion events and World Bosses.
Tormented Lord Zir
Stygian Stones x 2
Exquisite Blood x 27
Swipe to scroll horizontally
Lord Zir Loot Table
General
Barbarian
Druid
Necromancer
Rogue
Sorcerer
Diadem of the Ancient Helm Cosmetic
Ramaladni’s Magnum Opus
Mad Wolf’s Glee
Blood Artisan’s Cuirass
Grasp of Shadow
Staff of Endless Rage
Penitent Greaves
Rage of Harrogath
Vasily’s Prayer
Deathless Visage
Eyes in the Dark
Iceheart Brais
Razorplate
Gohr’s Devastating Grips
Greatstaff of the Crone
Greaves of the Empty Tomb
Skyhunter
Raiment of the Infinite
Temerity
Overkill
Fleshrender
Lidless Wall
Asheara’s Khanjar
Esadora’s Overflowing Cameo
Yen’s Blessing
The Butcher’s Cleaver
The Butcher’s Cleaver
Cruor’s Embrace
Scoundrel’s Kiss
Fractured Winterglass
Row 5 – Cell 0
Arreat’s Bearing
Wildheart Hunger
Row 5 – Cell 3
Row 5 – Cell 4
Row 5 – Cell 5
The Beast in the Ice
Stack up Cold Resistance for Beast in the Ice (Image credit: Jennifer Young – Windows Central)
The Beast in the Ice will inflict, yes you guessed it, Cold damage. So stack those Sapphire gems and chug a Cold elixir for this fight.
Where to find The Beast in the Ice
(Image credit: Jennifer Young – Windows Central)
The Beast in the Ice’s location is classed as a Nightmare Dungeon. Therefore, you’ll need to collect Distilled Fear and use this at the Occultist to craft a sigil. This will open The Glacial Fissure which is located South-west of Kyovashad in the Fractured Peaks
How to summon The Beast in the Ice
Distilled Fear x 9 Used to craft a Glacial Fissure Sigil at the Occultist
Distilled Fear drops from Nightmare Dungeons Tier 30 and above
Tormented Beast in the Ice
Stygian Stones x 2
Distilled Fear x 27
Swipe to scroll horizontally
The Beast in the Ice Loot Table
General
Barbarian
Druid
Necromancer
Rogue
Sorcerer
Binding the Fell Steed (Cosmetic)
Fields of Crimson
Insatiable Fury
Bloodless Scream
Condemnation
Staff of Lam Esen
Skull Torch (Cosmetic)
100,000 Steps
Hunter’s Zenith
Howl from Below
Word of Hakan
Esu’s Heirloom
Frostburn
Ancients’ Oath
Waxing Gibbous
Deathspeaker’s Pendant
Windforce
Gloves of the Illuminator
Mother’s Embrace
Battle Trance
Storm’s Companion
Ring of Mendeln
Eaglehorn
The Oculus
Fists of Fate
Hellhammer
Unsung Ascetic’s Wraps
Mutilator Plate
Beastfall Boots
Starfall Coronet
Tassets of the Dawning Sky
Ring of the Ravenous
Row 5 – Cell 2
Row 5 – Cell 3
Row 5 – Cell 4
Row 5 – Cell 5
Paingorger’s Gauntlets
Row 6 – Cell 1
Row 6 – Cell 2
Row 6 – Cell 3
Row 6 – Cell 4
Row 6 – Cell 5
Duriel, King of Maggots
(Image credit: Blizzard)
Duriel, who made a fleeting appearance in the campaign, and who also featured as a boss in Diablo 2: Resurrected, returns in the endgame. He will inflict Poison damage so stack Emeralds and a Poison Elixir to max out your poison resistance.
Where to find Duriel
(Image credit: Jennifer Young Windows Central)
The Gaping Crevasse to the East of Gea Kul in Kehjistan.
How to summon Duriel
To summon Duriel, you’ll need to have fought Varshan and Grigoire. Note that only the player that summoned these bosses will have the necessary materials dropped, but can summon for the entire group. You can also drop materials you have for another person in your party.
Mucus Slick Eggs x 2 (from Varshan)
Shards of Agony x 2 (from Grigoire)
Tormented Duriel
Stygian Stones x 2
Mucus Slick Eggs x 6 (from Varshan)
Shards of Agony x 6 (from Grigoire)
Swipe to scroll horizontally
Duriel, King of Maggots Loot Table
General
Barbarian
Druid
Necromancer
Rogue
Sorcerer
Smoldering Brimstone Mount
Azurewrath
Tempest Roar
Black River
Cowl of the Nameless
Flamescar
Godslayer Crown
Tuskhelm of Joritz the Mighty
Dolmen Stone
Blood Moon Breeches
Scoundrel’s Leathers
Blue Rose
Flickerstep
Row 2 – Cell 1
Row 2 – Cell 2
Row 2 – Cell 3
Row 2 – Cell 4
Row 2 – Cell 5
Tibault’s Will
Row 3 – Cell 1
Row 3 – Cell 2
Row 3 – Cell 3
Row 3 – Cell 4
Row 3 – Cell 5
X’Fal’s Corroded Signet
Row 4 – Cell 1
Row 4 – Cell 2
Row 4 – Cell 3
Row 4 – Cell 4
Row 4 – Cell 5
Soulbrand
Row 5 – Cell 1
Row 5 – Cell 2
Row 5 – Cell 3
Row 5 – Cell 4
Row 5 – Cell 5
Banished Lord’s Talisman
Row 6 – Cell 1
Row 6 – Cell 2
Row 6 – Cell 3
Row 6 – Cell 4
Row 6 – Cell 5
Swipe to scroll horizontally
Duriel Uber Uniques
General
Barbarian
Druid
Necromancer
Rogue
Sorcerer
Melted Heart of Selig
Doombringer
Ahavarion, Spear of Lycander
Doombringer
Doombringer
Ahavarion, Spear of Lycander
Andariel’s Visage
The Grandfather
Row 1 – Cell 2
The Grandfather
Row 1 – Cell 4
Row 1 – Cell 5
Harlequin Crest
Row 2 – Cell 1
Row 2 – Cell 2
Row 2 – Cell 3
Row 2 – Cell 4
Row 2 – Cell 5
Tyrael’s Might
Row 3 – Cell 1
Row 3 – Cell 2
Row 3 – Cell 3
Row 3 – Cell 4
Row 3 – Cell 5
Ring of Starless Skies (
Row 4 – Cell 1
Row 4 – Cell 2
Row 4 – Cell 3
Row 4 – Cell 4
Row 4 – Cell 5
Row 5 – Cell 0
Row 5 – Cell 1
Row 5 – Cell 2
Row 5 – Cell 3
Row 5 – Cell 4
Row 5 – Cell 5
Andariel, Maiden of Anguish
Andariel is being added to the Boss Ladder (Image credit: Blizzard Entertainment)
Andariel is a new boss for Season 4, available in both Eternal and Seasonal Realms. Andariel is Duriel’s twin, therefore they have identical loot tables. Both Andariel and Duriel will be your main source of Uber Uniques.
Andariel will inflict all damage types, so go for an ‘all resistance’ gem in your gear with Diamonds.
Where to find Andariel
Andariel is lurking at the Hanged Man’s Hall (Image credit: Jennifer Young – Windows Central)
Hanged Man’s Hall to the East of Tarsarak
How to summon Andariel
You’ll need to have fought both The Beast in the Ice and Zir for the materials required to summon Andariel.
Pincushioned Doll x 2 (From Beast in the Ice)
Sandscorched Shackles x 2 (From Lord Zir)
Tormented Andariel
Stygian Stones x 2
Pincushioned Doll x 6 (From Beast in the Ice)
Sandscorched Shackles x 6 (From Lord Zir)
Swipe to scroll horizontally
Andariel Loot Table
General
Barbarian
Druid
Necromancer
Rogue
Sorcerer
Smoldering Brimstone Mount
Azurewrath
Tempest Roar
Black River
Cowl of the Nameless
Flamescar
Godslayer Crown
Tuskhelm of Joritz the Mighty
Dolmen Stone
Blood Moon Breeches
Scoundrel’s Leathers
Blue Rose
Flickerstep
Row 2 – Cell 1
Row 2 – Cell 2
Row 2 – Cell 3
Row 2 – Cell 4
Row 2 – Cell 5
Tibault’s Will
Row 3 – Cell 1
Row 3 – Cell 2
Row 3 – Cell 3
Row 3 – Cell 4
Row 3 – Cell 5
X’Fal’s Corroded Signet
Row 4 – Cell 1
Row 4 – Cell 2
Row 4 – Cell 3
Row 4 – Cell 4
Row 4 – Cell 5
Soulbrand
Row 5 – Cell 1
Row 5 – Cell 2
Row 5 – Cell 3
Row 5 – Cell 4
Row 5 – Cell 5
Banished Lord’s Talisman
Row 6 – Cell 1
Row 6 – Cell 2
Row 6 – Cell 3
Row 6 – Cell 4
Row 6 – Cell 5
Swipe to scroll horizontally
Andariel Uber Uniques
General
Barbarian
Druid
Necromancer
Rogue
Sorcerer
Melted Heart of Selig
Doombringer
Ahavarion, Spear of Lycander
Doombringer
Doombringer
Ahavarion, Spear of Lycander
Andariel’s Visage
The Grandfather
Row 1 – Cell 2
The Grandfather
Row 1 – Cell 4
Row 1 – Cell 5
Harlequin Crest
Row 2 – Cell 1
Row 2 – Cell 2
Row 2 – Cell 3
Row 2 – Cell 4
Row 2 – Cell 5
Tyrael’s Might
Row 3 – Cell 1
Row 3 – Cell 2
Row 3 – Cell 3
Row 3 – Cell 4
Row 3 – Cell 5
Ring of Starless Skies (
Row 4 – Cell 1
Row 4 – Cell 2
Row 4 – Cell 3
Row 4 – Cell 4
Row 4 – Cell 5
Row 5 – Cell 0
Row 5 – Cell 1
Row 5 – Cell 2
Row 5 – Cell 3
Row 5 – Cell 4
Row 5 – Cell 5
Echo of Lilith
(Image credit: Blizzard)
Lilith isn’t technically part of the Boss Ladder, and isn’t worth farming for Uniques and materials, however as a ‘Pinnacle Boss’ she is worth fighting at least once each Season as she will drop a Respelendent Spark when first defeated.
Resplendent Sparks are incredibly rare crafting materials used to craft Uber Uniques.
Where to find Uber Lilith
(Image credit: Jennifer Young – Windows Central)
Uber Lilith can be found in World Tier 4 at the Nevesk Church, go and meet Mommy at level 100 and with a perfected build. Uber Lilith is by far the toughest of all the bosses.